Charlotte’s Web And UCB Begin Sleep And Anxiety Study

A cannabidiol (CBD) wellness producer is collaborating with a Colorado university on a new study on sleep quality and anxiety.

Boulder-based Charlotte’s Web Holdings (CWH) on Wednesday announced a preclinical sleep and anxiety study with its CW Labs division and the University of Colorado Boulder’s (UCB) Research and Education Addressing Cannabis and Health (REACH) Center.

The study will utilize full-spectrum CBD and cannabinol (CBN) hemp formulations with a delta-9 tetrahydrocannabinol content of less than 0.03 percent.

Charlotte’s Web formulations will be the only ones used in the study.

“Charlotte’s Web is committed to advancing science on the benefits and safety of CBD and other hemp phytocannabinoids through rigorous scientific investigations such as this sleep and anxiety study,” says Charlotte’s Web Senior Vice President Tim Orr. “We’re honored to team up with CU’s REACH Center to explore the potential impacts of full-spectrum hemp extract with CBD and CBN on anxiety and sleep quality.”

A Need For Scientific Evidence

According to CWH, there is currently a lack of published preclinical and clinical data on phytocannabinoids other than CBD and THC and their effect levels available in commercially available hemp-derived CBD supplements.

CWH says there is some anecdotal evidence that CBN can help with sleep, but it is unsubstantiated by clinical and preclinical evidence to validate such claims.

Professor of Integrative Physiology at UCB Monika Fleshner, Ph.D. Says there is a great need for properly controlled experiments designed to test potential neural and physiological impacts of hemp-derived phytocannabinoids.

“With support from CU Reach and Charlotte’s Web,” says Fleshner. “Our research will explore the efficacy and mechanisms of how these substances can affect complex brain-mediated behavior, such as disturbed sleep.”

According to CHW, a long-term expectation of the study is that it will inform future clinical initiatives to create a better understanding of how specific cannabinoid ratios and various delivery methods can effectively support improved sleep quality and instill a healthier sleep architecture in people.